:root{color-scheme:dark;--bg:#0b1421;--panel:#101c2b;--panel2:#142234;--border:#263648;--text:#e8f1f7;--muted:#8fa4b5;--teal:#6de0cc;--orange:#f2b66b;--blue:#74b7f2;--red:#ef777b;--radius:13px;font-family:Inter,"Noto Sans SC","Microsoft YaHei",system-ui,sans-serif;font-synthesis:none}
*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:var(--bg);color:var(--text);font-size:15px;line-height:1.5}button,input,select{font:inherit}button{cursor:pointer}a{color:var(--teal);text-decoration:none}a:hover{text-decoration:underline}button:focus-visible,input:focus-visible,select:focus-visible,a:focus-visible{outline:2px solid var(--teal);outline-offset:2px}[hidden]{display:none!important}
.app-shell{min-height:100vh;display:flex;flex-direction:column}.topbar{height:72px;padding:0 24px;display:flex;align-items:center;gap:30px;border-bottom:1px solid var(--border);background:#0d1927;flex:none}.brand{display:flex;align-items:center;gap:12px;min-width:278px}.brand-mark{position:relative;display:grid;place-items:center;width:37px;height:37px;border:1px solid #4da99e;border-radius:10px;color:var(--teal);font-size:25px;font-weight:800;line-height:1}.brand-node{position:absolute;right:3px;bottom:4px;width:7px;height:7px;border-radius:50%;background:var(--orange)}.brand strong{display:block;letter-spacing:.12em;font-size:16px;line-height:1.15}.brand strong span{color:var(--teal)}.brand small{display:block;margin-top:4px;color:var(--muted);font-size:12px;letter-spacing:.08em}.top-stats{display:flex;align-items:center;gap:26px;margin-left:auto}.top-stats>div{display:flex;align-items:baseline;gap:7px}.top-stats strong{font-size:19px;letter-spacing:-.04em;font-variant-numeric:tabular-nums}.top-stats span{font-size:12px;color:var(--muted)}.about-link{font-size:13px;color:#b7c9d5;white-space:nowrap;margin-left:14px}
.workspace{min-height:calc(100vh - 72px);display:grid;grid-template-columns:290px minmax(360px,1fr) 368px}.controls,.inspector{background:var(--panel);overflow-y:auto;min-height:0}.controls{border-right:1px solid var(--border);padding:25px 19px 28px}.inspector{border-left:1px solid var(--border)}.sidebar-head{padding:0 4px 20px;border-bottom:1px solid var(--border)}.eyebrow,.graph-kicker,.detail-kicker{color:var(--teal);font-size:11px;font-weight:800;letter-spacing:.17em}.sidebar-head h1{font-size:23px;line-height:1.2;margin:9px 0}.sidebar-head p{font-size:13px;line-height:1.6;color:var(--muted);margin:0}.control-block{position:relative;padding:20px 4px 18px;border-bottom:1px solid var(--border)}.control-block>label:not(.check-row),.block-title{display:flex;align-items:center;justify-content:space-between;margin-bottom:10px;font-size:13px;font-weight:700;color:#cddbe5}.control-block select,.search-wrap{width:100%;height:40px;border:1px solid #35485b;border-radius:8px;background:#0d1927;color:var(--text)}.control-block select{padding:0 31px 0 11px;appearance:none;background-image:url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' width='12' height='8'%3E%3Cpath d='m1 1 5 5 5-5' stroke='%238fa4b5' stroke-width='1.5' fill='none'/%3E%3C/svg%3E");background-repeat:no-repeat;background-position:right 12px center}.search-wrap{display:flex;align-items:center;padding:0 10px;gap:8px}.search-wrap span{color:var(--teal);font-size:24px;line-height:1;transform:rotate(-20deg)}.search-wrap input{outline:none;border:0;background:transparent;color:var(--text);width:100%;min-width:0;font-size:14px}.search-wrap input::placeholder{color:#708697}.search-results{position:absolute;top:73px;left:4px;right:4px;z-index:10;border:1px solid #3b5367;border-radius:9px;max-height:320px;overflow-y:auto;background:#162638;box-shadow:0 18px 50px #0008}.search-result{display:block;width:100%;padding:10px 12px;border:0;border-bottom:1px solid #2a3b4b;text-align:left;background:transparent;color:var(--text)}.search-result:hover,.search-result:focus-visible{background:#203a4c}.search-result strong{display:block;color:var(--teal);font-size:13px}.search-result span{display:block;color:#bacbd6;font-size:12px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.search-empty{padding:13px;color:var(--muted);font-size:13px}.control-help{font-size:12px;color:var(--muted);line-height:1.6;margin:10px 0 0}.text-button{border:0;background:transparent;color:var(--teal);font-size:12px;padding:2px 0}.text-button:hover{text-decoration:underline}.check-row{display:flex;align-items:center;gap:9px;padding:8px 0;color:#d2e0e9;font-size:13px;cursor:pointer}.check-row input{accent-color:var(--teal);width:15px;height:15px;margin:0}.check-row em{margin-left:auto;color:var(--muted);font-size:11px;font-style:normal;font-variant-numeric:tabular-nums}.layer-swatch{width:17px;height:3px;flex:none;border-radius:3px}.layer-swatch.structure{background:var(--orange)}.layer-swatch.string{background:#8e9cae}.layer-swatch.domain{background:var(--blue)}.category-list{display:grid;gap:3px}.category-button{display:flex;align-items:center;gap:9px;border:1px solid transparent;border-radius:7px;background:transparent;color:#b9cbd6;padding:7px;width:100%;text-align:left;font-size:12px}.category-button:hover,.category-button.active{background:#1d3342;border-color:#355c61;color:#fff}.category-dot{width:9px;height:9px;border-radius:50%;flex:none}.category-button em{margin-left:auto;font-size:11px;color:#8196a6;font-style:normal}.method-note{margin:22px 4px 0;padding:14px;border:1px solid #34514e;background:#132a31;border-radius:10px}.method-note strong{display:block;font-size:13px;color:#b7efe3}.method-note p{margin:6px 0 0;color:#a8bdc5;font-size:12px;line-height:1.65}
.graph-panel{position:relative;min-width:0;overflow:hidden;background:radial-gradient(circle at 52% 43%,#142a38 0,#101f30 35%,#0b1725 72%)}.graph-panel:before{content:"";position:absolute;inset:0;pointer-events:none;opacity:.2;background-image:linear-gradient(#5b7990 1px,transparent 1px),linear-gradient(90deg,#5b7990 1px,transparent 1px);background-size:45px 45px;mask-image:radial-gradient(circle at center,#000,transparent 76%)}.graph-toolbar,.graph-footer{position:absolute;z-index:2;left:0;right:0;display:flex;justify-content:space-between;align-items:center;pointer-events:none}.graph-toolbar{top:0;padding:18px 20px;background:linear-gradient(#0b1725d9,transparent)}.graph-tools{display:flex;align-items:center;gap:8px;color:#a8bac8;font-size:12px}.graph-tools button{pointer-events:auto;border:1px solid #395064;background:#172b3d;color:#ddecf3;border-radius:7px;width:31px;height:31px;font-size:20px;line-height:1}.graph-tools button:hover{border-color:var(--teal);color:var(--teal)}.graph-footer{bottom:0;padding:19px 20px;background:linear-gradient(transparent,#0b1725d9);color:#93a9b8;font-size:11px}.gesture-icon{color:var(--teal);font-style:normal;margin-right:4px}#graph{display:block;width:100%;height:100%;touch-action:none;cursor:grab;position:relative}#graph.dragging{cursor:grabbing}.graph-tooltip{position:absolute;z-index:4;pointer-events:none;max-width:230px;background:#233748;border:1px solid #527081;color:#fff;border-radius:8px;padding:8px 10px;box-shadow:0 10px 30px #0009;font-size:12px}.graph-tooltip strong{display:block;color:var(--teal)}.graph-tooltip span{display:block;color:#d6e5ec}.loading{position:absolute;inset:0;display:flex;align-items:center;justify-content:center;gap:10px;background:#0d1b2ad9;color:#d5e7ee;font-size:14px;z-index:3}.loader{width:20px;height:20px;border:2px solid #496877;border-top-color:var(--teal);border-radius:50%;animation:spin .8s linear infinite}@keyframes spin{to{transform:rotate(360deg)}}
.detail-empty{padding:85px 34px;text-align:center;color:var(--muted)}.detail-empty-icon{font-size:40px;color:var(--teal);margin-bottom:12px}.detail-empty strong{display:block;font-size:17px;color:var(--text)}.detail-empty p{font-size:13px;line-height:1.7}.detail{padding:0 22px 32px}.detail-head{padding:24px 0 18px;border-bottom:1px solid var(--border)}.detail-id-row{display:flex;justify-content:space-between;align-items:flex-start;gap:12px}.detail h2{font-size:25px;line-height:1.2;margin:7px 0 8px;letter-spacing:-.03em}.detail-product{margin:0;color:#d4e3eb;font-size:15px;line-height:1.45}.icon-button{border:1px solid #3a5365;border-radius:7px;background:#1a2b3b;color:#b8d8dc;font-size:13px;padding:5px 8px}.icon-button:hover{color:var(--teal);border-color:var(--teal)}.detail-subline{display:flex;flex-wrap:wrap;gap:6px;margin-top:13px}.tag{display:inline-flex;padding:4px 8px;border-radius:5px;border:1px solid #354859;background:#17283a;color:#bcd0dc;font-size:11px;line-height:1.2}.tag.teal{border-color:#327d76;background:#153a3d;color:#9bebd8}.tag.orange{border-color:#785a3c;background:#3b2b24;color:#ffd092}.section{padding:20px 0;border-bottom:1px solid var(--border)}.section h3{display:flex;justify-content:space-between;align-items:center;margin:0 0 13px;font-size:14px;letter-spacing:.01em}.section h3 small{color:var(--muted);font-weight:400;font-size:11px}.kv{display:grid;grid-template-columns:105px minmax(0,1fr);gap:9px 8px;font-size:12px;margin:8px 0}.kv dt{color:var(--muted)}.kv dd{margin:0;color:#e2eef3;min-width:0;overflow-wrap:anywhere}.kv dd a{color:var(--teal)}.structure-box{height:230px;border:1px solid #345064;border-radius:10px;position:relative;background:radial-gradient(circle at center,#203951,#111f30 70%);overflow:hidden}.structure-box .viewer{position:absolute;inset:0}.structure-overlay{position:absolute;inset:0;display:flex;flex-direction:column;align-items:center;justify-content:center;gap:12px;padding:15px;text-align:center;background:#122336dc}.structure-overlay span{font-size:12px;color:#b5cad4;line-height:1.5}.primary-button{border:1px solid #49a79c;background:#276a69;border-radius:7px;color:#ebfffb;padding:8px 13px;font-size:13px;font-weight:700}.primary-button:hover{background:#317f79}.structure-links{display:flex;gap:16px;margin-top:9px;font-size:12px}.structure-none{display:grid;place-items:center;height:150px;border:1px dashed #40556a;border-radius:9px;color:var(--muted);font-size:12px;text-align:center;padding:14px}.rna-value{font-variant-numeric:tabular-nums}.rna-value.up{color:#ff9a96}.rna-value.down{color:#90c6fb}.rna-value.neutral{color:#b6c6d1}.evidence-card{display:flex;justify-content:space-between;align-items:flex-start;gap:10px;padding:10px 0;border-bottom:1px solid #263747}.evidence-card:last-child{border:0}.evidence-card button{display:block;text-align:left;border:0;padding:0;background:transparent;color:var(--teal);font-size:13px;font-weight:700}.evidence-card button:hover{text-decoration:underline}.evidence-card span{display:block;color:#aebfca;font-size:11px;max-width:195px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.evidence-card em{color:var(--orange);font-style:normal;font-size:11px;white-space:nowrap}.sequence-details summary{cursor:pointer;color:#cde1e9;font-size:13px}.sequence-details pre{white-space:pre-wrap;word-break:break-all;font:12px/1.55 ui-monospace,SFMono-Regular,Consolas,monospace;color:#a9cbd5;background:#0b1927;padding:10px;border-radius:7px;max-height:170px;overflow:auto}.detail-foot{font-size:11px;line-height:1.55;color:#8199a8;margin-top:20px}
@media(max-width:1190px){.workspace{grid-template-columns:250px minmax(320px,1fr) 330px}.controls{padding-left:14px;padding-right:14px}.topbar{padding:0 16px}.brand{min-width:245px}.top-stats{gap:14px}.detail{padding-left:17px;padding-right:17px}}
@media(max-width:980px){.workspace{grid-template-columns:250px minmax(320px,1fr);grid-template-rows:minmax(580px,calc(100vh - 72px)) auto}.controls{grid-row:1 / 3}.inspector{grid-column:2;border-left:0;border-top:1px solid var(--border);overflow:visible}.graph-panel{grid-column:2}.top-stats>div:nth-child(2){display:none}}
@media(max-width:680px){.topbar{height:64px;gap:8px}.brand{min-width:0}.brand strong{font-size:14px}.brand small{font-size:10px}.top-stats{display:none}.about-link{margin-left:auto;font-size:12px}.workspace{display:flex;flex-direction:column;min-height:0}.controls{order:1;overflow:visible;padding:14px 16px;border-right:0;border-bottom:1px solid var(--border)}.sidebar-head{padding-bottom:12px}.sidebar-head h1{font-size:19px}.sidebar-head p{display:none}.control-block{padding:12px 2px}.category-block,.method-note{display:none}.graph-panel{order:2;height:65vh;min-height:430px;flex:none}.inspector{order:3}.graph-footer{font-size:10px;padding:13px 12px}.graph-toolbar{padding:13px}.graph-kicker{font-size:10px}.detail{padding:0 16px 26px}}
.evidence-card>div{min-width:0;flex:1}
.evidence-card em{white-space:normal;text-align:right;max-width:120px;flex:none}
@media(max-width:680px){.controls,.graph-panel,.inspector{width:100%;min-width:0}.graph-panel canvas{min-width:0}}
#comparison-summary,#comparison-direction{white-space:pre-line}